Endocrine Abstracts

Background: Isolated pituitary stalk (PS) lesions/thickening detected on imaging pose challenging dilemmas.Aim: Audit the diagnostic approach and management of patients with isolated PS lesions/thickening reported on MRI in a tertiary hospital.Methods: Reports of pituitary/brain MRIs performed in our Radiology Department between 1/2013 and 12/2015 were searched for the terms ‘stalk’, ‘infundibular’, ‘infund...

The diagnosis of Cushing’s Syndrome (CS) requires demonstration of excess circulating cortisol. Measurement of late night salivary cortisol (LNSF) has been advocated as a simple, non-invasive and reliable outpatient diagnostic tool for patients with suspected CS but the usefulness of its metabolite cortisone (LNSE) remains unclear. LNSE levels are approximately six times higher than LNSF in saliva due to the rapid action of 11β-hydroxysteroid dehydrogenase type 2 (11...

Introduction: TSH-stimulated serum thyroglobulin (Tg) is used as a sensitive marker for the detection of early recurrence or residual disease following treatment for differentiated thyroid cancer (DTC). However, stimulated Tg, using TSH or thyroid hormone withdrawal, is either costly or cumbersome for patients.Aim: To compare the performance of basal T4 suppressed, with stimulated Tg measurement, in the follow up of patients treated for DTC.</...